Products and Services

• WGS involves sequencing the entire genome, while WES involves sequencing only the exome.
• WGS typically generates more data than WES, since it involves sequencing the entire genome.
• WGS can be used to identify all the genetic variations in the genome, including variants present in non-coding and structural portions, while WES is primarily used to identify variations in protein-coding portions of the genome
• WGS is typically more expensive and time-consuming than WES since it involves sequencing a larger portion of the genome.

• WGS typically has a coverage of 30X. This means that on average, each base in the genome is covered by 30 reads. This is considered a high coverage and allows for the detection of rare variants and structural variations.
• WES, on the other hand, has a coverage of 100X. This means that on average, each base in the exome (the protein-coding regions of the genome) is covered by 100 reads. This is considered the best coverage which allows for the detection of rare variants on single nucleotide polymorphisms (SNPs) with more accuracy.

Dante Genomics provides several types of raw data for Whole Genome Sequencing, including:

• FASTQ: this file format is the product of primary bioinformatic analysis and contains the raw sequencing data, including the base calls and quality scores for each read. It is a standard format used in next-generation sequencing and can be used to analyze the data using various bioinformatics tools, leading to secondary bioinformatic analysis products such as BAM and VCF files.
• VCF: this file format contains the variant calls, or differences between the individual's genome and a reference genome. It includes information such as the type of variant, the location in the genome, and any associated annotation data.
• BAM: This file format is a binary version of a SAM (Sequence Alignment/Map) file, which contains the aligned reads of the sequencing data to a reference genome. It is usually used for downstream analysis such as variant calling and annotation.

Yes, Dante Genomics offers white labeling of their products.

White labeling is a process in which a product or service is made by one company but is branded and sold by another company under a different name. This means that Dante Genomics can provide their Whole Genome Sequencing services to other companies or organizations, and they can rebrand and sell it as their own service. This can be useful for companies that want to offer genetic testing services without having to invest in the necessary infrastructure or expertise.

Yes, at Dante Genomics, the logistics costs are included in the price. This means that the company covers all the costs associated with the shipping and handling of the samples, including the costs of the collection kits, shipping materials, and shipping fees. This can make the process of obtaining DNA samples much more convenient and cost-effective for the customer.

The turnaround time for results at Dante Genomics is typically 4 weeks.

The Turnaround Time starts from when your sample is received at the lab and it is meant in working days (1 week is formed by 5 working days, 4 weeks are meant as 28 working days). Our labs process samples from Monday to Friday. This is an approximate turnaround time; it may vary depending on the volume of samples and the complexity of the analysis.

“Clinically validated actionable insights" is significant in the interpretation and utilization of genetic test results because it ensures that the information provided is accurate, reliable, and useful for making medical decisions.

It means that the genetic test results are analyzed and interpreted based on evidence from clinical studies and research, rather than just raw data. Additionally, the insights provided can be used to inform treatment options, risk assessments, and other medical decisions, thus making the test results actionable. This is particularly important in the field of genetics, where the information provided can have a significant impact on an individual's health.

By ensuring that the genetic test results are clinically validated and actionable, it helps healthcare professionals and patients make informed decisions about their health, which can ultimately lead to better health outcomes.

Dante Genomics offers the possibility to perform whole genome sequencing on a wide range of species (plants, animals, fungi, bacteria ecc.) with all types of raw data as deliverables.

If you are looking for secondary bioinformatic analysis to be performed, please provide us with the reference genome to perform alignment or at least the species of the source material, so that we can check the most updated databases.
Our preference is to receive blood, saliva or pre-extracted DNA as source material. If you are planning to send other types, please contact customer.support@dantelabs.com for further assistance.

Our standard pipeline uses Grch37 as reference genome.

We can also provide Grch38 alignment under specific request.

Dante Genomics serves multiple types of customers, including:

• Researchers: this group of customers includes scientists and researchers from universities, research institutions, and biotechnology companies who use the genetic information provided by Dante Genomics for their studies and research projects.
• Individuals: Dante Genomics also serves individuals who are interested in understanding their genetic makeup for personal reasons, such as understanding their risk for certain diseases or identifying carrier status for inherited conditions.
• Concierge Doctors: Concierge doctors are private doctors who offer personalized and proactive medical care to their patients. They often order genetic testing as part of their service to offer more personalized medical care to their patients.
• Hospitals and Clinics: Dante Genomics also works with hospitals and clinics that have genetics department or that offer genetic testing as part of their services.
• Rare Disease Organizations: Dante Genomics also works with organizations that focus on rare diseases, they use genetic testing as a tool to help diagnose and understand the genetic basis of rare diseases.
  

All these customers use the genetic information provided by Dante Genomics to improve healthcare and to gain a better understanding of genetics.