Provides full genome coverage
Most genetics studies have demonstrated correlations between Parkinson’s disease and a wide range of mutations, occurring both in coding and non-coding regions of the genome:
- single-nucleotide variants (SNVs), located in intronic regions.
- structural genomic variations, including copy number variations (CNVs), that affect multiple human PD phenotypes.
- alterations in intergenic regions of the genome.
- mutations in noncoding regulatory regions.
- small genomic deletions or gains that affect regulatory regions.
Only Whole Genome Sequencing can detect the small regions of such structural variations with high resolution, providing full genome coverage and the most comprehensive, accurate, and precise test for diagnosing medical conditions or understanding predispositions to diseases. In case of common gene panels, the lack of complete coverage results in incomplete information.
